Joined were blown away as they went in at half-time four objectives down without precedent for a Premier League game, making it very simple for the Reds as Naby Keita and Diogo Jota were on track before Salah struck twice.
The superb Salah finished his full go-around from the get-go in the subsequent half, taking his objective count for the season to 15, preceding substitute Pogba was excused for a helpless test on Keita.
Salah has now scored in 10 successive games and Liverpool is unbeaten in 21 matches, while United is in disorder after the most reprimanding of losses in their terrace.
Keita hushed the United dependable when he exploited poor safeguarding to slide past David de Gea with his right foot in the wake of being sneaked in by Salah.
That strike in the fifth moment was the Reds' soonest at Old Trafford in the Premier League and they didn't have long to hang tight briefly, Trent Alexander-Arnold's cross giving Jota a tap-in after a mistake between Harry Maguire and Luke Shaw.
Liverpool, as of now without the harmed Fabinho, lost James Milner halfway through the primary half yet Salah put them far away with a twofold before the break after Alisson had denied Mason Greenwood.
The horrifying Red Devils were everywhere and savage Egypt forward made them pay, wrapping up with his right foot when he was selected by Keita and tucking home with his left from short proximity not long before a half-time whistle that was welcomed with noisy boos.
Salah finished his treble five minutes into the subsequent half, hustling onto Jordan Henderson's sharp pass before beating De Gea with a clinical left-foot finish after Cristiano Ronaldo had an objective precluded for offside.
Joined's day got ugly when Pogba was excused for a foolish jump on Keita following a VAR check, having initially been shown a yellow card on the hour mark.
Keita couldn't proceed and the United players appear as though they would prefer not, as just a splendid save from De Gea prevented Alexander-Arnold from adding a 6th.
Andrew Robertson's square sent the ball running into the crossbar late on to keep Edinson Cavani from tracking down the rear of the net and there were unavoidably more boos at the last whistle to end an uneven challenge.
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