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In An Extremely Rare Case A Woman's Immune System Clears HIV Virus

An HIV-positive Argentinian lady has made news for being only the second known individual whose immune system may have eliminated the virus from their body without the need of medications or treatment. Doctors ran testing on more than a billion of the woman's cells and discovered no viable indication of HIV infection, according to a case study published in Archives of Internal Medicine.

These findings suggest that a sterilising cure may be an exceedingly unusual, but conceivable, consequence of HIV-1 infection, hey stated. The unnamed woman was diagnosed with HIV-1 in 2013 and was dubbed the "Esperanza patient" (after her city). Eight years later, follow-up exams and various commercial viral load tests verified that she had no signs of active HIV infection or HIV-1-associated illness. According to Avert, HIV-1 is the most prevalent kind of HIV and accounts for around 95% of all infections globally. HIV-2, on the other hand, is less frequent and less contagious than HIV-1.

According to the World Health Organization (WHO), 37.7 million persons worldwide were infected with HIV as of 2020. According to statistics, 62 percent of HIV patients in South Africa were taking antiretroviral therapy (ART) in 2018. There have been stories in recent years of patients with HIV being able to suppress the virus without the use of ARTs, but with the aid of stem cell transplantation. They were dubbed elite controllers. Cases in the headlines include the "Berlin patient" and the "London patient," both of whom survived HIV with the aid of stem cell transplants, which were initially intended to destroy cancer cells.

In the case of the Berlin patient, Timothy Ray Brown, who was diagnosed with HIV in 1995, the transplant suddenly "cured" him. Even without ARTs, the transplant placed the virus into long-term remission, to the point that it could no longer be identified. The London patient, Adam Castillejo, was diagnosed with HIV in 2003 and no longer required daily ARTs after getting donor stem-cell therapy, which he also got for cancer.

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Archives of Internal Medicine Argentinian Esperanza HIV HIV-positive


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