Van Zyl was brought into the world in Salisbury, Southern Rhodesia now Harare, Zimbabwe. She went to the University of Pretoria where she acquired a BSc in human physiology and brain science, and a Bachelor of Medicine, Bachelor of Surgery degree . Dr Sindisiwe Van Zyl interned at Chris Hani Baragwanath Hospital.In 2004, she wedded Marinus van Zyl.
She utilized Twitter, mostly, to educate and connect with about HIV especially Prevention of mother to kid transmission. She likewise showed up habitually on TV, radio and other media platforms. She shared about her own excursion with sorrow and doctor burnout.Dr. van Zyl chronicled how she lost 41 kg while on a Banting diet. She was a characteristic short sleeper needing around 4 hours of rest each night while working normally. Her logical exploration has included rules to help HIV-influenced people and couples to accomplish pregnancy safely and COVID-19 and HIV co-infection.She held different jobs in the South African Medical Association.Because of her broad general wellbeing support, she was known as the "individuals' doctor".
Writer for Health24,Bona magazine, Choma magazine
Radio DJ Kaya FM
Visitor craftsman in the drama 7de Laan
On 10 April 2021, she passed on at 45 years old from COVID-19.
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